A Review of Progress on Targeting LDL Receptor-Dependent and -Independent Pathways for the Treatment of Hypercholesterolemia, a Major Risk Factor of ASCVD

Since the discovery of the LDL receptor in 1973 by Brown and Goldstein as a causative protein in hypercholesterolemia, tremendous amounts of effort have gone into finding ways to manage high LDL cholesterol in familial hypercholesterolemic (HoFH and HeFH) individuals with loss-of-function mutations...

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Detalles Bibliográficos
Autor principal: Srivastava, Rai Ajit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297381/
https://www.ncbi.nlm.nih.gov/pubmed/37371118
http://dx.doi.org/10.3390/cells12121648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297381/
https://www.ncbi.nlm.nih.gov/pubmed/37371118
http://dx.doi.org/10.3390/cells12121648

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