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Pressure Clamping During Ocular Perfusions Drives Nitric Oxide-Mediated Washout

PURPOSE: The aim of this study was to test the hypothesis that nitric oxide (NO) mediates a pressure-dependent, negative feedback loop that maintains conventional outflow homeostasis and thus IOP. If true, holding pressure during ocular perfusions will result in uncontrolled production of NO, hyper-...

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Detalles Bibliográficos
Autores principales: Kelly, Ruth A., McDonnell, Fiona S., De Ieso, Michael L., Overby, Darryl R., Stamer, W. Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297780/
https://www.ncbi.nlm.nih.gov/pubmed/37358489
http://dx.doi.org/10.1167/iovs.64.7.36