Impact of IDH Mutations, the 1p/19q Co-Deletion and the G-CIMP Status on Alternative Splicing in Diffuse Gliomas

By generating protein diversity, alternative splicing provides an important oncogenic pathway. Isocitrate dehydrogenase (IDH) 1 and 2 mutations and 1p/19q co-deletion have become crucial for the novel molecular classification of diffuse gliomas, which also incorporates DNA methylation profiling. In...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Fritah, Sabrina, Nazarov, Petr V., Kaoma, Tony, Van Dyck, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297931/
https://www.ncbi.nlm.nih.gov/pubmed/37372972
http://dx.doi.org/10.3390/ijms24129825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297931/
https://www.ncbi.nlm.nih.gov/pubmed/37372972
http://dx.doi.org/10.3390/ijms24129825

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