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Meg8-DMR as the Secondary Regulatory Region Regulates the Expression of MicroRNAs While It Does Not Affect Embryonic Development in Mice

Meg8-DMR is the first maternal methylated DMR to be discovered in the imprinted Dlk1-Dio3 domain. The deletion of Meg8-DMR enhances the migration and invasion of MLTC-1 depending on the CTCF binding sites. However, the biological function of Meg8-DMR during mouse development remains unknown. In this...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Han, Zhengbin, He, Hongjuan, Zhang, Ximeijia, Zhang, Mengyan, Li, Boran, Wu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298023/
https://www.ncbi.nlm.nih.gov/pubmed/37372444
http://dx.doi.org/10.3390/genes14061264