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USP15-USP7 Axis and UBE2T Differential Expression May Predict Pathogenesis and Poor Prognosis in De Novo Myelodysplastic Neoplasm

The aim of this study was to evaluate the expression of USP7, USP15, UBE2O, and UBE2T genes in Myelodysplastic neoplasm (MDS) to identify possible targets of ubiquitination and deubiquitination in MDS pathobiology. To achieve this, eight datasets from the Gene Expression Omnibus (GEO) database were...

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Detalles Bibliográficos
Autores principales: de Carvalho, Luiz Gustavo Almeida, Komoto, Tatiana Takahasi, Moreno, Daniel Antunes, Goes, João Vitor Caetano, de Oliveira, Roberta Taiane Germano, de Lima Melo, Mayara Magna, Roa, Mariela Estefany Gislene Vera, Gonçalves, Paola Gyuliane, Montefusco-Pereira, Carlos Victor, Pinheiro, Ronald Feitosa, Ribeiro Junior, Howard Lopes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298103/
https://www.ncbi.nlm.nih.gov/pubmed/37373211
http://dx.doi.org/10.3390/ijms241210058