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Fatty Acid Desaturation Is Suppressed in Mir-26a/b Knockout Goat Mammary Epithelial Cells by Upregulating INSIG1

MicroRNA-26 (miR-26a and miR-26b) plays a critical role in lipid metabolism, but its endogenous regulatory mechanism in fatty acid metabolism is not clear in goat mammary epithelial cells (GMECs). GMECs with the simultaneous knockout of miR-26a and miR-26b were obtained using the CRISPR/Cas9 system...

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Detalles Bibliográficos
Autores principales: Zhu, Lu, Jiao, Hongyun, Gao, Wenchang, Huang, Lian, Shi, Chenbo, Zhang, Fuhong, Wu, Jiao, Luo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298109/
https://www.ncbi.nlm.nih.gov/pubmed/37373175
http://dx.doi.org/10.3390/ijms241210028