Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases

A class-A GPCR dopamine D2 receptor (D2R) plays a critical role in the proper functioning of neuronal circuits through the downstream activation of both G-protein- and β-arrestin-dependent signaling pathways. Understanding the signaling pathways downstream of D2R is critical for developing effective...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Haiping, Ma, Haixiang, Zeng, Xingyue, Wu, Chengyan, Acharya, Srijan, Sudan, Sarabjeet Kour, Zhang, Xiaohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298151/
https://www.ncbi.nlm.nih.gov/pubmed/37373182
http://dx.doi.org/10.3390/ijms241210031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298151/
https://www.ncbi.nlm.nih.gov/pubmed/37373182
http://dx.doi.org/10.3390/ijms241210031

Ejemplares similares