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The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina Propria

The bladder urothelium releases ATP into the lamina propria (LP) during filling, which can activate P2X receptors on afferent neurons and trigger the micturition reflex. Effective ATP concentrations are largely dependent on metabolism by membrane-bound and soluble ectonucleotidases (s-ENTDs), and th...

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Detalles Bibliográficos
Autores principales: Aresta Branco, Mafalda S. L., Gutierrez Cruz, Alejandro, Peri, Lauren E., Mutafova-Yambolieva, Violeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298213/
https://www.ncbi.nlm.nih.gov/pubmed/37373111
http://dx.doi.org/10.3390/ijms24129964