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Novel Model of Oxalate Diet-Induced Chronic Kidney Disease in Dahl-Salt-Sensitive Rats

Diet-induced models of chronic kidney disease (CKD) offer several advantages, including clinical relevance and animal welfare, compared with surgical models. Oxalate is a plant-based, terminal toxic metabolite that is eliminated by the kidneys through glomerular filtration and tubular secretion. An...

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Detalles Bibliográficos
Autores principales: Dube, Prabhatchandra, Aradhyula, Vaishnavi, Lad, Apurva, Khalaf, Fatimah K., Breidenbach, Joshua D., Kashaboina, Eshita, Gorthi, Snigdha, Varatharajan, Shangari, Stevens, Travis W., Connolly, Jacob A., Soehnlen, Sophia M., Sood, Ambika, Marellapudi, Amulya, Ranabothu, Meghana, Kleinhenz, Andrew L., Domenig, Oliver, Dworkin, Lance D., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298248/
https://www.ncbi.nlm.nih.gov/pubmed/37373209
http://dx.doi.org/10.3390/ijms241210062