Propranolol-Loaded Limonene-Based Microemulsion Thermo-Responsive Mucoadhesive Nasal Nanogel: Design, In Vitro Assessment, Ex Vivo Permeation, and Brain Biodistribution

Propranolol is the first-line drug for managing migraine attacks. D-limonene is a citrus oil known for its neuroprotective mechanism. Thus, the current work aims to design a thermo-responsive intranasal limonene-based microemulsion mucoadhesive nanogel to improve propranolol efficacy. Microemulsion...

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Detalles Bibliográficos
Autores principales: Abla, Kawthar K., Domiati, Souraya, El Majzoub, Rania, Mehanna, Mohammed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298266/
https://www.ncbi.nlm.nih.gov/pubmed/37367161
http://dx.doi.org/10.3390/gels9060491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298266/
https://www.ncbi.nlm.nih.gov/pubmed/37367161
http://dx.doi.org/10.3390/gels9060491

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