p53 Dysregulation in Breast Cancer: Insights on Mutations in the TP53 Network and p53 Isoform Expression

In breast cancer, p53 expression levels are better predictors of outcome and chemotherapy response than TP53 mutation. Several molecular mechanisms that modulate p53 levels and functions, including p53 isoform expression, have been described, and may contribute to deregulated p53 activities and wors...

Descripción completa

Detalles Bibliográficos
Autores principales: Steffens Reinhardt, Luiza, Groen, Kira, Xavier, Alexandre, Avery-Kiejda, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298268/
https://www.ncbi.nlm.nih.gov/pubmed/37373225
http://dx.doi.org/10.3390/ijms241210078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298268/
https://www.ncbi.nlm.nih.gov/pubmed/37373225
http://dx.doi.org/10.3390/ijms241210078

Ejemplares similares