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Histone Deacetylases (HDAC) Inhibitor—Valproic Acid Sensitizes Human Melanoma Cells to Dacarbazine and PARP Inhibitor

The inhibition of histone deacetylases (HDACs) holds promise as a potential anti-cancer therapy as histone and non-histone protein acetylation is frequently disrupted in cancer, leading to cancer initiation and progression. Additionally, the use of a histone deacetylase inhibitor (HDACi) such as the...

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Detalles Bibliográficos
Autores principales: Drzewiecka, Małgorzata, Gajos-Michniewicz, Anna, Hoser, Grażyna, Jaśniak, Dominika, Barszczewska-Pietraszek, Gabriela, Sitarek, Przemysław, Czarny, Piotr, Piekarski, Janusz, Radek, Maciej, Czyż, Małgorzata, Skorski, Tomasz, Śliwiński, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298302/
https://www.ncbi.nlm.nih.gov/pubmed/37372475
http://dx.doi.org/10.3390/genes14061295