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Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism

Cystathionine γ-lyase (CSE) is an enzyme responsible for the biosynthesis of cysteine from cystathionine in the final step of the transsulfuration pathway. It also has β-lyase activity toward cystine, generating cysteine persulfide (Cys-SSH). The chemical reactivity of Cys-SSH is thought to be invol...

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Detalles Bibliográficos
Autores principales: Araki, Shoma, Takata, Tsuyoshi, Ono, Katsuhiko, Sawa, Tomohiro, Kasamatsu, Shingo, Ihara, Hideshi, Kumagai, Yoshito, Akaike, Takaaki, Watanabe, Yasuo, Tsuchiya, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298322/
https://www.ncbi.nlm.nih.gov/pubmed/37373128
http://dx.doi.org/10.3390/ijms24129982