Natural Compound Boldine Lessens Myotonic Dystrophy Type 1 Phenotypes in DM1 Drosophila Models, Patient-Derived Cell Lines, and HSA(LR) Mice

Myotonic dystrophy type 1 (DM1) is a complex rare disorder characterized by progressive muscle dysfunction, involving weakness, myotonia, and wasting, but also exhibiting additional clinical signs in multiple organs and systems. Central dysregulation, caused by an expansion of a CTG trinucleotide re...

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Detalles Bibliográficos
Autores principales: Álvarez-Abril, Mari Carmen, García-Alcover, Irma, Colonques-Bellmunt, Jordi, Garijo, Raquel, Pérez-Alonso, Manuel, Artero, Rubén, López-Castel, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298378/
https://www.ncbi.nlm.nih.gov/pubmed/37372969
http://dx.doi.org/10.3390/ijms24129820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298378/
https://www.ncbi.nlm.nih.gov/pubmed/37372969
http://dx.doi.org/10.3390/ijms24129820

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