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Developing Biomimetic Hydrogels of the Arterial Wall as a Prothrombotic Substrate for In Vitro Human Thrombosis Models

Current in vitro thrombosis models utilise simplistic 2D surfaces coated with purified components of the subendothelial matrix. The lack of a realistic humanised model has led to greater study of thrombus formation in in vivo tests in animals. Here we aimed to develop 3D hydrogel-based replicas of t...

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Detalles Bibliográficos
Autores principales: Ranjbar, Jacob, Njoroge, Wanjiku, Gibbins, Jonathan M., Roach, Paul, Yang, Ying, Harper, Alan G. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298383/
https://www.ncbi.nlm.nih.gov/pubmed/37367147
http://dx.doi.org/10.3390/gels9060477