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High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients

Background: Homologous recombination repair (HR) is the most accurate repair pathway for double-strand breaks and replication fork disruption that is capable of faithfully restoring the original nucleotide sequence of the broken DNA. The deficiency of this mechanism is a frequent event in tumorigene...

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Detalles Bibliográficos
Autores principales: Azambuja, Daniel de Barcellos, e Gloria, Helena de Castro, Montenegro, Gabriel e Silva, Kalil, Antonio Nocchi, Hoffmann, Jean-Sébastien, Leguisamo, Natalia Motta, Saffi, Jenifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298388/
https://www.ncbi.nlm.nih.gov/pubmed/37372450
http://dx.doi.org/10.3390/genes14061270