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Potential Prognostic Value of GATA4 Depends on the p53 Expression in Primary Glioblastoma Patients

Background: Primary glioblastoma is characterized by an extremely poor prognosis. The promoter methylation of GATA4 leads to the loss of its expression in many cancer types. The formation of high-grade astrocytomas can be promoted by the concurrent loss of TP53 and GATA4 in normal human astrocytes....

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Detalles Bibliográficos
Autores principales: Trąbska-Kluch, Berenika, Braun, Marcin, Orzechowska, Magdalena, Paszek, Sylwia, Zuchowska, Alina, Sołek, Julia, Kluska, Adam, Fijuth, Jacek, Jesionek-Kupnicka, Dorota, Zawlik, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298403/
https://www.ncbi.nlm.nih.gov/pubmed/37372326
http://dx.doi.org/10.3390/genes14061146