Microsatellite Instability and Immune Response: From Microenvironment Features to Therapeutic Actionability—Lessons from Colorectal Cancer

Microsatellite instability (MSI) can be found in 15–20% of all colorectal cancers (CRC) and is the key feature of a defective DNA mismatch repair (MMR) system. Currently, MSI has been established as a unique and pivotal biomarker in the diagnosis, prognosis, and treatment of CRC. MSI tumors display...

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Detalles Bibliográficos
Autores principales: Greco, Luana, Rubbino, Federica, Dal Buono, Arianna, Laghi, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298406/
https://www.ncbi.nlm.nih.gov/pubmed/37372349
http://dx.doi.org/10.3390/genes14061169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298406/
https://www.ncbi.nlm.nih.gov/pubmed/37372349
http://dx.doi.org/10.3390/genes14061169

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