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Single-Cell Transcriptome Analysis Identifies Subclusters with Inflammatory Fibroblast Responses in Localized Scleroderma

Localized scleroderma (LS) is an autoimmune disease with both inflammatory and fibrotic components causing an abnormal deposition of collagen in the skin and underlying tissue, often leading to disfigurement and disability. Much of its pathophysiology is extrapolated from systemic sclerosis (SSc) si...

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Detalles Bibliográficos
Autores principales: Werner, Giffin, Sanyal, Anwesha, Mirizio, Emily, Hutchins, Theresa, Tabib, Tracy, Lafyatis, Robert, Jacobe, Heidi, Torok, Kathryn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298454/
https://www.ncbi.nlm.nih.gov/pubmed/37372943
http://dx.doi.org/10.3390/ijms24129796