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HDAC6 Deficiency Has Moderate Effects on Behaviors and Parkinson’s Disease Pathology in Mice

Histone deacetylase 6 (HDAC6) is involved in the regulation of protein aggregation and neuroinflammation, but its role in Parkinson’s disease (PD) remains controversial. In this study, Hdac6(−/−) mice were generated by CRISPR-Cas9 technology for exploring the effect of HDAC6 on the pathological prog...

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Detalles Bibliográficos
Autores principales: Zhao, Jiayin, He, Yongtao, Duan, Yufei, Ma, Yuanyuan, Dong, Hongtian, Zhang, Xiaoshuang, Fang, Rong, Zhang, Yunhe, Yu, Mei, Huang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298689/
https://www.ncbi.nlm.nih.gov/pubmed/37373121
http://dx.doi.org/10.3390/ijms24129975