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HDAC6 Deficiency Has Moderate Effects on Behaviors and Parkinson’s Disease Pathology in Mice
Histone deacetylase 6 (HDAC6) is involved in the regulation of protein aggregation and neuroinflammation, but its role in Parkinson’s disease (PD) remains controversial. In this study, Hdac6(−/−) mice were generated by CRISPR-Cas9 technology for exploring the effect of HDAC6 on the pathological prog...
Autores principales: | Zhao, Jiayin, He, Yongtao, Duan, Yufei, Ma, Yuanyuan, Dong, Hongtian, Zhang, Xiaoshuang, Fang, Rong, Zhang, Yunhe, Yu, Mei, Huang, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298689/ https://www.ncbi.nlm.nih.gov/pubmed/37373121 http://dx.doi.org/10.3390/ijms24129975 |
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