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PAK1 copy number in breast cancer—Associations with proliferation and molecular subtypes

INTRODUCTION: P21-activated kinase 1 (PAK1) is known to be overexpressed in several human tumour types, including breast cancer (BC). It is located on chromosome 11 (11q13.5-q14.1) and plays a significant role in proliferation in BC. In this study we aimed to assess PAK1 gene copy number (CN) in pri...

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Detalles Bibliográficos
Autores principales: Skjervold, Anette H., Valla, Marit, Ytterhus, Borgny, Bofin, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298784/
https://www.ncbi.nlm.nih.gov/pubmed/37368917
http://dx.doi.org/10.1371/journal.pone.0287608