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Epidermal Loss of RORα Enhances Skin Inflammation in a MC903-Induced Mouse Model of Atopic Dermatitis

Atopic dermatitis (AD) is a chronic inflammatory skin disease featuring skin barrier dysfunction and immune dysregulation. Previously, we reported that the retinoid-related orphan nuclear receptor RORα was highly expressed in the epidermis of normal skin. We also found that it positively regulated t...

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Detalles Bibliográficos
Autores principales: Hua, Xiangmei, Blosch, Conrad Dean, Dorsey, Hannah, Ficaro, Maria K., Wallace, Nicole L., Hsung, Richard P., Dai, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298918/
https://www.ncbi.nlm.nih.gov/pubmed/37373387
http://dx.doi.org/10.3390/ijms241210241