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Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners

SPOP (Speckle-type POZ protein) is an E3 ubiquitin ligase adaptor protein that mediates the ubiquitination of several substrates. Furthermore, SPOP is responsible for the regulation of both degradable and nondegradable polyubiquitination of a number of substrates with diverse biological functions. T...

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Detalles Bibliográficos
Autores principales: Diop, Awa, Pietrangeli, Paola, Nardella, Caterina, Pennacchietti, Valeria, Pagano, Livia, Toto, Angelo, Di Felice, Mariana, Di Matteo, Sara, Marcocci, Lucia, Malagrinò, Francesca, Gianni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298926/
https://www.ncbi.nlm.nih.gov/pubmed/37373284
http://dx.doi.org/10.3390/ijms241210138