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Antiangiogenic Effect of Dopamine and Dopaminergic Agonists as an Adjuvant Therapeutic Option in the Treatment of Cancer, Endometriosis, and Osteoarthritis

Dopamine (DA) and dopamine agonists (DA-Ag) have shown antiangiogenic potential through the vascular endothelial growth factor (VEGF) pathway. They inhibit VEGF and VEGF receptor 2 (VEGFR 2) functions through the dopamine receptor D2 (D2R), preventing important angiogenesis-related processes such as...

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Detalles Bibliográficos
Autores principales: Mendoza-Torreblanca, Julieta Griselda, Cárdenas-Rodríguez, Noemi, Carro-Rodríguez, Jazmín, Contreras-García, Itzel Jatziri, Garciadiego-Cázares, David, Ortega-Cuellar, Daniel, Martínez-López, Valentín, Alfaro-Rodríguez, Alfonso, Evia-Ramírez, Alberto Nayib, Ignacio-Mejía, Iván, Vargas-Hernández, Marco Antonio, Bandala, Cindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299003/
https://www.ncbi.nlm.nih.gov/pubmed/37373348
http://dx.doi.org/10.3390/ijms241210199