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Activity of FAAH-Inhibitor JZP327A in an Experimental Rat Model of Migraine

Increased anandamide levels via fatty acid amide hydrolase (FAAH) inhibition can decrease the pronociceptive responses and inflammatory mediators in animal models of migraine. Here, we profile the pharmacological activity of the FAAH inhibitor JZP327A, a chiral 1,3,4-oxadiazol-2(3H)-one compound, in...

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Detalles Bibliográficos
Autores principales: Greco, Rosaria, Francavilla, Miriam, Demartini, Chiara, Zanaboni, Anna Maria, Facchetti, Sara, Palmisani, Michela, Franco, Valentina, Tassorelli, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299064/
https://www.ncbi.nlm.nih.gov/pubmed/37373250
http://dx.doi.org/10.3390/ijms241210102