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Single-Molecule Analysis of the Improved Variants of the G-Quadruplex Recognition Protein G4P

As many as 700,000 unique sequences in the human genome are predicted to fold into G-quadruplexes (G4s), non-canonical structures formed by Hoogsteen guanine–guanine pairing within G-rich nucleic acids. G4s play both physiological and pathological roles in many vital cellular processes including DNA...

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Detalles Bibliográficos
Autores principales: Gaur, Paras, Bain, Fletcher E., Honda, Masayoshi, Granger, Sophie L., Spies, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299155/
https://www.ncbi.nlm.nih.gov/pubmed/37373425
http://dx.doi.org/10.3390/ijms241210274