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Role of the IL-33/ST2 Activation Pathway in the Development of the Hepatic Fibrosis Induced by Schistosoma mansoni Granulomas in Mice

Schistosoma mansoni eggs retained in host tissues induce innate cytokine release, contributing to the induction of Type-2 immune responses and granuloma formation, important to restrain cytotoxic antigens, but leading to fibrosis. Interleukin(IL)-33 participates in experimental models of inflammatio...

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Detalles Bibliográficos
Autores principales: Maggi, Laura, Camelo, Genil Mororó Araújo, Rocha, Izabella Chrystina, Pereira Alves, William, Moreira, João Marcelo Peixoto, Almeida Pereira, Thiago, Tafuri, Wagner Luiz, Rabelo, Élida Mara Leite, Correa, Ary, Ecco, Roselene, Negrão-Corrêa, Deborah Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299179/
https://www.ncbi.nlm.nih.gov/pubmed/37373379
http://dx.doi.org/10.3390/ijms241210237