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Role of the IL-33/ST2 Activation Pathway in the Development of the Hepatic Fibrosis Induced by Schistosoma mansoni Granulomas in Mice
Schistosoma mansoni eggs retained in host tissues induce innate cytokine release, contributing to the induction of Type-2 immune responses and granuloma formation, important to restrain cytotoxic antigens, but leading to fibrosis. Interleukin(IL)-33 participates in experimental models of inflammatio...
Autores principales: | Maggi, Laura, Camelo, Genil Mororó Araújo, Rocha, Izabella Chrystina, Pereira Alves, William, Moreira, João Marcelo Peixoto, Almeida Pereira, Thiago, Tafuri, Wagner Luiz, Rabelo, Élida Mara Leite, Correa, Ary, Ecco, Roselene, Negrão-Corrêa, Deborah Aparecida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299179/ https://www.ncbi.nlm.nih.gov/pubmed/37373379 http://dx.doi.org/10.3390/ijms241210237 |
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