Cargando…

Tg(Δ113p53:cmyc) Transgene Upregulates glut1 Expression to Promote Zebrafish Heart Regeneration

The heart switches its main metabolic substrate from glucose to fatty acids shortly after birth, which is one of reasons for the loss of heart regeneration capability in adult mammals. On the contrary, metabolic shifts from oxidative phosphorylation to glucose metabolism promote cardiomyocyte (CM) p...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Zimu, Wang, Kaiyuan, Lo, Lijian, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299255/
https://www.ncbi.nlm.nih.gov/pubmed/37367411
http://dx.doi.org/10.3390/jcdd10060246