Posttranslational Modification of Human Cytochrome CYP4F11 by 4-Hydroxynonenal Impairs ω-Hydroxylation in Malaria Pigment Hemozoin-Fed Monocytes: The Role in Malaria Immunosuppression

Malaria is a frequent parasitic infection becomes life threatening due to the disequilibrated immune responses of the host. Avid phagocytosis of malarial pigment hemozoin (HZ) and HZ-containing Plasmodium parasites incapacitates monocyte functions by bioactive lipoperoxidation products 4-hydroxynone...

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Detalles Bibliográficos
Autores principales: Skorokhod, Oleksii, Triglione, Vincenzo, Barrera, Valentina, Di Nardo, Giovanna, Valente, Elena, Ulliers, Daniela, Schwarzer, Evelin, Gilardi, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299294/
https://www.ncbi.nlm.nih.gov/pubmed/37373382
http://dx.doi.org/10.3390/ijms241210232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299294/
https://www.ncbi.nlm.nih.gov/pubmed/37373382
http://dx.doi.org/10.3390/ijms241210232

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