COX5A Alleviates Doxorubicin-Induced Cardiotoxicity by Suppressing Oxidative Stress, Mitochondrial Dysfunction and Cardiomyocyte Apoptosis

Doxorubicin (DOX) as a chemotherapeutic agent can cause mitochondrial dysfunction and heart failure. COX5A has been described as an important regulator of mitochondrial energy metabolism. We investigate the roles of COX5A in DOX-induced cardiomyopathy and explore the underlying mechanisms. C57BL/6J...

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Detalles Bibliográficos
Autores principales: Zhang, Peipei, Lu, Hao, Wu, Yuan, Lu, Danbo, Li, Chenguang, Yang, Xiangdong, Chen, Zhangwei, Qian, Juying, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299295/
https://www.ncbi.nlm.nih.gov/pubmed/37373547
http://dx.doi.org/10.3390/ijms241210400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299295/
https://www.ncbi.nlm.nih.gov/pubmed/37373547
http://dx.doi.org/10.3390/ijms241210400

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