Less Severe Polymicrobial Sepsis in Conditional mgmt-Deleted Mice Using LysM-Cre System, Impacts of DNA Methylation and MGMT Inhibitor in Sepsis

The O6-methylguanine-DNA methyltransferase (MGMT) is a DNA suicide repair enzyme that might be important during sepsis but has never been explored. Then, the proteomic analysis of lipopolysaccharide (LPS)-stimulated wild-type (WT) macrophages increased proteasome proteins and reduced oxidative phosp...

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Detalles Bibliográficos
Autores principales: Sae-khow, Kritsanawan, Phuengmaung, Pornpimol, Issara-Amphorn, Jiraphorn, Makjaroen, Jiradej, Visitchanakun, Peerapat, Boonmee, Atsadang, Benjaskulluecha, Salisa, Palaga, Tanapat, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299382/
https://www.ncbi.nlm.nih.gov/pubmed/37373325
http://dx.doi.org/10.3390/ijms241210175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299382/
https://www.ncbi.nlm.nih.gov/pubmed/37373325
http://dx.doi.org/10.3390/ijms241210175

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