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Less Severe Polymicrobial Sepsis in Conditional mgmt-Deleted Mice Using LysM-Cre System, Impacts of DNA Methylation and MGMT Inhibitor in Sepsis
The O6-methylguanine-DNA methyltransferase (MGMT) is a DNA suicide repair enzyme that might be important during sepsis but has never been explored. Then, the proteomic analysis of lipopolysaccharide (LPS)-stimulated wild-type (WT) macrophages increased proteasome proteins and reduced oxidative phosp...
Autores principales: | Sae-khow, Kritsanawan, Phuengmaung, Pornpimol, Issara-Amphorn, Jiraphorn, Makjaroen, Jiradej, Visitchanakun, Peerapat, Boonmee, Atsadang, Benjaskulluecha, Salisa, Palaga, Tanapat, Leelahavanichkul, Asada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299382/ https://www.ncbi.nlm.nih.gov/pubmed/37373325 http://dx.doi.org/10.3390/ijms241210175 |
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