Evidence-Based Guide to Using Artificial Introns for Tissue-Specific Knockout in Mice

Up until recently, methods for generating floxed mice either conventionally or by CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas9 (CRISPR-associated protein 9) editing have been technically challenging, expensive and error-prone, or time-consuming. To circumvent these issues,...

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Detalles Bibliográficos
Autores principales: McBeath, Elena, Fujiwara, Keigi, Hofmann, Marie-Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299402/
https://www.ncbi.nlm.nih.gov/pubmed/37373404
http://dx.doi.org/10.3390/ijms241210258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299402/
https://www.ncbi.nlm.nih.gov/pubmed/37373404
http://dx.doi.org/10.3390/ijms241210258

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