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NOTCH Signaling in Mantle Cell Lymphoma: Biological and Clinical Implications

Despite major progress in mantle cell lymphoma (MCL) therapeutics, MCL remains a deadly disease with a median survival not exceeding four years. No single driver genetic lesion has been described to solely give rise to MCL. The hallmark translocation t(11;14)(q13;q32) requires additional genetic alt...

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Detalles Bibliográficos
Autores principales: Deshotels, Leigh, Safa, Firas M., Saba, Nakhle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299455/
https://www.ncbi.nlm.nih.gov/pubmed/37373427
http://dx.doi.org/10.3390/ijms241210280