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Five-Aminolevulinic Acid (5-ALA) Induces Heme Oxygenase-1 and Ameliorates Palmitic Acid-Induced Endoplasmic Reticulum Stress in Renal Tubules

Steatosis, or ectopic lipid deposition, is the fundamental pathophysiology of non-alcoholic steatohepatitis and chronic kidney disease. Steatosis in the renal tubule causes endoplasmic reticulum (ER) stress, leading to kidney injury. Thus, ER stress could be a therapeutic target in steatonephropathy...

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Detalles Bibliográficos
Autores principales: Hamada, Shintaro, Mae, Yukari, Takata, Tomoaki, Hanada, Hinako, Kubo, Misaki, Taniguchi, Sosuke, Iyama, Takuji, Sugihara, Takaaki, Isomoto, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299457/
https://www.ncbi.nlm.nih.gov/pubmed/37373300
http://dx.doi.org/10.3390/ijms241210151