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In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals

Cancer therapy with clinically established anticancer drugs is frequently hampered by the development of drug resistance of tumors and severe side effects in normal organs and tissues. The demand for powerful, but less toxic, drugs is high. Phytochemicals represent an important reservoir for drug de...

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Detalles Bibliográficos
Autores principales: Schäfer, Julia, Klösgen, Vincent Julius, Omer, Ejlal A., Kadioglu, Onat, Mbaveng, Armelle T., Kuete, Victor, Hildebrandt, Andreas, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299530/
https://www.ncbi.nlm.nih.gov/pubmed/37373385
http://dx.doi.org/10.3390/ijms241210240