A New, Convenient Way to Fully Substituted α,β-Unsaturated γ-Hydroxy Butyrolactams

The synthesis of novel, highly functionalized 5-hydroxy 3-pyrrolin-2-ones via a two-step procedure involving an addition reaction between KCN and corresponding chalcones, followed by ring condensation of the obtained β-cyano ketones with het(aryl)aldehydes under basic conditions is described. This p...

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Detalles Bibliográficos
Autores principales: Aksenov, Alexander V., Aksenov, Dmitrii A., Kurenkov, Igor A., Leontiev, Alexander V., Aksenov, Nicolai A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299564/
https://www.ncbi.nlm.nih.gov/pubmed/37373361
http://dx.doi.org/10.3390/ijms241210213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299564/
https://www.ncbi.nlm.nih.gov/pubmed/37373361
http://dx.doi.org/10.3390/ijms241210213

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