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Proteolytic Resistance Determines Albumin Nanoparticle Drug Delivery Properties and Increases Cathepsin B, D, and G Expression

Proteolytic activity is pivotal in maintaining cell homeostasis and function. In pathological conditions such as cancer, it covers a key role in tumor cell viability, spreading to distant organs, and response to the treatment. Endosomes represent one of the major sites of cellular proteolytic activi...

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Detalles Bibliográficos
Autores principales: Kolesova, Ekaterina P., Egorova, Vera S., Syrocheva, Anastasiia O., Frolova, Anastasiia S., Kostyushev, Dmitry, Kostyusheva, Anastasiia, Brezgin, Sergey, Trushina, Daria B., Fatkhutdinova, Landysh, Zyuzin, Mikhail, Demina, Polina A., Khaydukov, Evgeny V., Zamyatnin, Andrey A., Parodi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299664/
https://www.ncbi.nlm.nih.gov/pubmed/37373389
http://dx.doi.org/10.3390/ijms241210245