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JAK/STAT as a Potential Therapeutic Target for Osteolytic Diseases

Several cytokines with major biological functions in inflammatory diseases exert their functions through the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signal transduction pathway. JAKs phosphorylate the cytoplasmic domain of the receptor, inducing the activation of i...

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Detalles Bibliográficos
Autores principales: Godoi, Mariely A., Camilli, Angelo C., Gonzales, Karen G. A., Costa, Vitória B., Papathanasiou, Evangelos, Leite, Fábio R. M., Guimarães-Stabili, Morgana R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299676/
https://www.ncbi.nlm.nih.gov/pubmed/37373437
http://dx.doi.org/10.3390/ijms241210290