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Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements

Analyses of genetic variation in many taxa have established that neutral genetic diversity is shaped by natural selection at linked sites. Whether the mode of selection is primarily the fixation of strongly beneficial alleles (selective sweeps) or purifying selection on deleterious mutations (backgr...

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Detalles Bibliográficos
Autores principales: Murphy, David A, Elyashiv, Eyal, Amster, Guy, Sella, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299832/
https://www.ncbi.nlm.nih.gov/pubmed/36196994
http://dx.doi.org/10.7554/eLife.76065