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A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule

Bacterial capsules have critical roles in host-pathogen interactions. They provide a protective envelope against host recognition, leading to immune evasion and bacterial survival. Here we define the capsule biosynthesis pathway of Haemophilus influenzae serotype b (Hib), a Gram-negative bacterium t...

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Detalles Bibliográficos
Autores principales: Cifuente, Javier O., Schulze, Julia, Bethe, Andrea, Di Domenico, Valerio, Litschko, Christa, Budde, Insa, Eidenberger, Lukas, Thiesler, Hauke, Ramón Roth, Isabel, Berger, Monika, Claus, Heike, D’Angelo, Cecilia, Marina, Alberto, Gerardy-Schahn, Rita, Schubert, Mario, Guerin, Marcelo E., Fiebig, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10299916/
https://www.ncbi.nlm.nih.gov/pubmed/37277468
http://dx.doi.org/10.1038/s41589-023-01324-3