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Shotgun proteomics identification of proteins expressed in the Descemet’s membrane of patients with Fuchs endothelial corneal dystrophy

Fuchs endothelial corneal dystrophy (FECD) is a slowly evolving, bilateral disease of the corneal endothelium, characterized by an abnormal accumulation of extracellular matrix (ECM) in the basement membrane (Descemet’s membrane, DM). This results in the formation of small round excrescences, called...

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Detalles Bibliográficos
Autores principales: Nakagawa, Tatsuya, Okumura, Naoki, Ikegawa, Masaya, Toyama, Yumiko, Nirasawa, Takashi, Mascarelli, Frederic, Vaitinadapoule, Hanielle, Aouimeur, Ines, He, Zhiguo, Gain, Philippe, Thuret, Gilles, Koizumi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300001/
https://www.ncbi.nlm.nih.gov/pubmed/37369713
http://dx.doi.org/10.1038/s41598-023-37104-1