Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer

The ubiquitin-proteasome system (UPS) controls protein turnover, and its dysfunction contributes to human diseases including cancer. Deubiquitinating enzymes (DUBs) remove ubiquitin from proteins to maintain their stability. Inhibition of DUBs could induce the degradation of selected oncoproteins an...

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Detalles Bibliográficos
Autores principales: Zhang, Yonghui, Du, Tongde, Liu, Na, Wang, Juan, Zhang, Lingqiang, Cui, Chun-Ping, Li, Chaonan, Zhang, Xin, Wu, Bo, Zhang, Jinhao, Jiang, Wenli, Zhang, Yubing, Zhang, Yuting, Li, Hongchang, Li, Peiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300026/
https://www.ncbi.nlm.nih.gov/pubmed/37369659
http://dx.doi.org/10.1038/s41419-023-05900-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300026/
https://www.ncbi.nlm.nih.gov/pubmed/37369659
http://dx.doi.org/10.1038/s41419-023-05900-2

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