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SOX1 acts as a tumor hypnotist rendering nasopharyngeal carcinoma cells refractory to chemotherapy

SOX1, a well-known tumor suppressor, delays malignant progression in most cancer types. However, high expression of SOX1 in late-stage head and neck squamous cell carcinoma leads to poor prognosis. In this study, we show that SOX1 induces nasopharyngeal carcinoma (NPC) cells to enter a quiescent sta...

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Detalles Bibliográficos
Autores principales: Lei, Xin-Xing, Wang, Shu-Lan, Xia, Ying, Yan, Min, He, Bin, Wang, Bo, Long, Zi-Jie, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300072/
https://www.ncbi.nlm.nih.gov/pubmed/37369660
http://dx.doi.org/10.1038/s41420-023-01479-x