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Chain-specificity of laminin α1-5 LG45 modules in the recognition of carbohydrate-linked receptors and intramolecular binding

Laminins are a family of heterotrimers composed of α-, β-, and γ-chains in the basement membrane. Five α chains contain laminin globular (LG) domain consisting of five tandem modules (LG1-5 modules) at their C-terminus. Each LG45 modules is connected to a compact cloverleaf-shaped structure of LG1-3...

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Detalles Bibliográficos
Autores principales: Matsunuma, Masumi, Kan, Ryuji, Yamada, Yuji, Hamada, Keisuke, Kanagawa, Motoi, Nomizu, Motoyoshi, Kikkawa, Yamato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300086/
https://www.ncbi.nlm.nih.gov/pubmed/37369727
http://dx.doi.org/10.1038/s41598-023-37533-y