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Drosophila mutants lacking the glial neurotransmitter-modifying enzyme Ebony exhibit low neurotransmitter levels and altered behavior

Inhibitors of enzymes that inactivate amine neurotransmitters (dopamine, serotonin), such as catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO), are thought to increase neurotransmitter levels and are widely used to treat Parkinson's disease and psychiatric disorders, yet the role...

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Detalles Bibliográficos
Autores principales: Pantalia, Meghan, Lin, Zhi, Tener, Samantha J., Qiao, Bing, Tang, Grace, Ulgherait, Matthew, O’Connor, Reed, Delventhal, Rebecca, Volpi, Julia, Syed, Sheyum, Itzhak, Nissim, Canman, Julie C., Fernández, María Paz, Shirasu-Hiza, Mimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300103/
https://www.ncbi.nlm.nih.gov/pubmed/37369755
http://dx.doi.org/10.1038/s41598-023-36558-7