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Microglial Galectin3 enhances endothelial metabolism and promotes pathological angiogenesis via Notch inhibition by competitively binding to Jag1

Microglia were considered as immune cells in inflammation until their angiogenic role was widely understood. Although the pro-inflammatory role of microglia in retinal angiogenesis has been explored, little is known about its role in pro-angiogenesis and the microglia–endothelia interaction. Here, w...

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Detalles Bibliográficos
Autores principales: Zhou, Zi-Yi, Chang, Tian-Fang, Lin, Zhi-Bin, Jing, Yu-Tong, Wen, Li-Shi, Niu, Ya-Li, Bai, Qian, Guo, Chang-Mei, Sun, Jia-Xing, Wang, Yu-Sheng, Dou, Guo-Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300109/
https://www.ncbi.nlm.nih.gov/pubmed/37369647
http://dx.doi.org/10.1038/s41419-023-05897-8