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Inhibition of TRPV4 remodels single cell polarity and suppresses the metastasis of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a malignant tumor, frequently causing both intrahepatic and extrahepatic metastases. The overall prognosis of patients with metastatic HCC is poor. Recently, single-cell (sc) polarity is proved to be an innate feature of some tumor cells in liquid phase, and directl...

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Detalles Bibliográficos
Autores principales: Liu, Jian, Guo, Yongjian, Zhang, Ruitian, Xu, Ye, Luo, Chengju, Wang, Rui, Xu, Shu, Wei, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300155/
https://www.ncbi.nlm.nih.gov/pubmed/37369706
http://dx.doi.org/10.1038/s41419-023-05903-z